0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

EFFECT OF CORTICOTROPHIN ON CHRONIC, SEVERE PRIMARY THROMBOCYTOPENIC PURPURA

ROBERT S. EVANS, M.D.; CHI KONG LIU, M.D.
AMA Arch Intern Med. 1951;88(4):503-506. doi:10.1001/archinte.1951.03810100087008.
Text Size: A A A
Published online

IDIOPATHIC thrombocytopenic purpura is one of the few disorders of obscure origin in which the effect of cortisone and corticotrophin (ACTH) therapy has not been extensively reported.1 Results of administration of the hormones will be difficult to evaluate since spontaneous remissions are common. In some patients, however, the disease runs a chronic, unremitting course, so that the effect of agents of possible therapeutic value is of greater significance. During the past four years we have had the opportunity of observing the disease in a most severe and persistent form in a woman, and we wish to report the dramatic effect of corticotrophin administration.

REPORT OF CASE  The patient (A. M.) was a 41-year-old married school teacher who was well until 1945, when she noted the appearance of spontaneous bruising and small hemorrhages in the skin, along with bleeding of the gums and frequent nosebleeds. These symptoms continued without remission

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();