In this book Dr. Bauer makes an attempt to look at the patient as a whole and to discourage the focusing of diagnostic attention on a single set of body systems. He tries to emphasize the need for understanding all the anatomic, physiologic, chemical and psychic disturbances that make the patient sick. The psychogenic factor is particularly stressed. He tries to urge better selection of laboratory tests so that the present tendency to tax both the patient's strength and his pocketbook to obtain a whole battery of data, much of which is noncontributory, can be avoided. There are two main divisions of the book. The first discusses leading signs; the second, leading symptoms. It is abundantly illustrated with cases drawn from the author's own clinical experience. It is a book that will appeal to most internists.