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GENERALIZED TORULOSIS WITH BONE INVOLVEMENT

MORRIS F. WIENER, M.D.
AMA Arch Intern Med. 1951;87(5):713-726. doi:10.1001/archinte.1951.03810050091009.
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A UNIQUE case of systemic torulosis is reported in which clinically demonstrable skeletal lesions proved to be, on postmortem study, torulosis granuloma of the bone marrow. No case is found in the literature in which definite osseous lesions are described, although the skeletal system is mentioned en passant as one of the rare sites of systemic Torula (Cryptococcus) invasion.

REPORT OF A CASE 

Present Illness.  —P. S. (R-2369), a 53 year old white man, was admitted to the Medical Service of the Veterans Administration Hospital, Miami Beach, Fla., on Sept. 10, 1946, complaining of persistent headache, insomnia and visual disturbance of one month's duration.

Previous History.  —In 1936, while in Colorado, he had an illness lasting about 30 days and manifested by fever, sweating, cough, anorexia and loss of weight. In 1937, when 44 years of age, he was hospitalized at Fitzsimons General Hospital, Denver, for about 75 days because

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