This symposium presents data contributed by fifty-four hospitals participating continued investigations on the applications and indications for the use of streptomycn. The Veterans Administration, the Army, the Navy, the United States Public Health Service, the Army Institute of Pathology, the National Research Council, the Food and Drug Administration, the American Trudeau Society and the National Tuberculosis Association are represented.
An excellent summary is presented, dealing with the development of resistance by the tubercle bacilli to various regimens of treatment with streptomycin. The toxicity and comparative effectiveness of streptomycin and dihydrostreptomycin are critically analyzed, and numerous protocols are included. It is concluded that considerable caution should be used in the administration of this antibiotic, and that disturbance of the eighth nerve, renal dysfunction, cutaneous manifestations and depression of bone marrow must be watched for.
The use of streptomycin in pulmonary, genitourinary, meningeal, miliary and extrapulmonary tuberculosis, as well as in various