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The Duodenal Glands of Brunner in Man, Their Distribution and Quantity: An Anatomical Study.

Arch Intern Med (Chic). 1947;79(5):587-588. doi:10.1001/archinte.1947.00220110127012.
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This is a detailed anatomic investigation of the location, arrangement and quantity of the duodenal glands of Brunner in man, based on the observations in 53 cadavers of all age classes examined by a gross staining technic. By direct observation of the stained duodenums in surface view and, after they were embedded in gelatin, in profile section, the author has elucidated the topography of the glands and has estimated the quantitative glandular density throughout the area. Histologic details other than the form of the glands and glandular islands have not been considered. Extensive descriptions accompanied with maps showing the extent of the area of the Brunner glands and the density of glandular distribution are given for each individual specimen.

The author has found that proximally the area of the Brunner glands borders along the pyloric ring, on which it gradually encroaches and frequently crosses with advancing age. The distal delimitation


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