0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

EFFECT OF ATROPINE ON THE BRANHAM SIGN IN ARTERIOVENOUS FISTULA

MILTON L. KRAMER; JACOB W. KAHN
Arch Intern Med (Chic). 1946;78(1):28-30. doi:10.1001/archinte.1946.00220010038003.
Text Size: A A A
Published online

THE BRANHAM1 sign is of proved value in the diagnosis of arteriovenous fistulas. It consists of a slowing of the pulse rate on temporary obliteration of the fistula. The response to obliteration is prompt, occurring within seconds, suggesting a reflex arc with the vagus nerve as the efferent limb. It would seem possible, therefore, to eliminate the Branham phenomenon in patients with arteriovenous fistulas by paralysis of the vagus nerve induced by atropine. This has been attempted previously with variable results.2 In the light of our experiences, this variability appears related only to the degree of completeness of the atropine effect attained.

PROCEDURE  The subjects were soldiers who had sustained wounds which led to the development of arteriovenous fistulas. A solution of atropine sulfate in distilled water was administered intravenously. The doses varied from 1.7 to 1.95 mg. of the drug. In an earlier case, the administration of

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 4

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();