This book has enjoyed the distinction of being the most popular one volume work on treatment since its first appearance in 1930. The author has periodically published new editions to keep the data abreast with the developments in therapy. This, the fifth edition, includes the newer advances in therapy. Clinical states which have become particularly important since the war, such as blast syndrome, chemical burns, airsickness, gas gangrene, human serum jaundice and shock, are discussed. Although some parts of the book have been rewritten, the method of presentation of the subject has remained unchanged. The reviewer recommends a consultation of this book whenever one wishes needed information on therapy. The book should continue to be one of the important books to be found in the library of any student or practicing physician.