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NEUROLOGIC COMPLICATIONS DURING MENINGOCOCCIC MENINGITIS TREATED WITH SULFONAMIDE DRUGS

THOMAS W. FARMER, MC-S, U.S.N.R.
Arch Intern Med (Chic). 1945;76(4):201-209. doi:10.1001/archinte.1945.00210340015002.
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The purpose of this presentation is to outline the clinical course and prognosis in a variety of neurologic complications of meningococcic meningitis. During the epidemic years of 1942, 1943 and 1944, approximately 300 cases of meningococcic meningitis were reviewed by me at four hospitals.1 About 100 cases involving children were included in this series. Of the 300 cases focal neurologic complications were observed to develop in 26 during the course of meningococcic infections. In each of these 26 cases it was ascertained that the paralysis did not exist before the onset of the meningeal infection and also that no other neurologic disease was present concomitantly with the meningitis. Detailed clinical information concerning the onset and severity of these sequelae was collected for this study.

An etiologic diagnosis was established in 24 of these 26 cases by the isolation of meningococci, group I, from the cerebrospinal fluid. In the remaining

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