This work is the result of painstaking study and research on the part of the author. The material was, obtained from 1,000 autopsies, 206 of which revealed endocardial disease. There are many photographs of specimens and of histologic sections throughout the book, serving to illustrate and emphasize concepts brought out by the author. A fairly successful attempt has been made to classify and to discuss all diseases of the endocardium from the point of view of etiology and pathologic anatomy. The bibliography is extensive and complete, covering the literature on the subject in different languages.