February 1943, Vol 71, No. 2 >

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ARTICLE | February 1943

ACTION OF DIGITALIS ON CONDUCTION IN THE SYNDROME OF SHORT PR INTERVAL AND PROLONGED QRS COMPLEX

THEODORE T. FOX, M.D.; JANET TRAVELL, M.D.; LEONARD MOLOFSKY, M.D.

Arch Intern Med (Chic). 1943;71(2):206-218. doi:10.1001/archinte.1943.00210020072005.

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It is stated that the effect of digitalis on the heart can simulate almost every type of electrocardiographic abnormality due to cardiac disorders with the exception of intraventricular conduction defects.¹ As far as the normal electrocardiogram is concerned, this statement is undoubtedly true. The observations of Hart,² however, have been widely cited in the literature as indicating that digitalis may occasionally cause a delay in intraventricular conduction and a consequent widening of the QRS complex.

In this study prolongation of the QRS time was produced by digitalis in the course of a clinical experiment. The observations were made in a case of so-called "bundle branch block with short PR interval," a syndrome first observed by Wilson³ and subsequently described by Wolff, Parkinson and White.⁴ Bishop⁵ more recently reviewed 45 cases of this syndrome reported in the literature, but as far as we are able to

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FOX TT, TRAVELL J, MOLOFSKY L. ACTION OF DIGITALIS ON CONDUCTION IN THE SYNDROME OF SHORT PR INTERVAL AND PROLONGED QRS COMPLEX. Arch Intern Med (Chic). 1943;71(2):206-218. doi:10.1001/archinte.1943.00210020072005.

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ACTION OF DIGITALIS ON CONDUCTION IN THE SYNDROME OF SHORT PR INTERVAL AND PROLONGED QRS COMPLEX

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