The changes in the twelfth edition of this established text consist primarily in the addition of approximately 50 pages of material concerning new therapeutic agents (sulfanilamide, hormones, vitamins) which have been developed in the four years that have elapsed since the eleventh edition. Complete alteration of the older subject matter has not been attempted, although minor changes have been made. The sketchiness with which some subjects are treated is explained in the prefacial statement, as well as by the further generalization that the constant increase in the scientifically recognized materia medica makes it difficult to combine the essentials of both experimental pharmacology and therapeutics in 900 pages. Certain "textbook errors" are perpetuated, especially those regarding the actions of drugs on man, errors originally arising from some unwarranted transfer of evidence from experiments on a single animal species.
Considered in its entirety the volume is a good text, the revision reasonably