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HYPERTHYROIDISM AND DIABETES

JAMES F. REGAN, M.D.; RUSSELL M. WILDER, M.D., Ph.D.
Arch Intern Med (Chic). 1940;65(6):1116-1122. doi:10.1001/archinte.1940.00190120033003.
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In 1926 one of us (Wilder1) reported a study of 38 cases of hyperthyroidism and diabetes. The patients were observed during the period from Jan. 1, 1923, to Dec. 31, 1925, inclusive. The present study is that of a series of patients seen during a similar period, from Jan. 1, 1935, to Dec. 31, 1937, inclusive. The patients in both series were divided into two groups—those with exophthalmic goiter, and those with adenomatous goiter and hyperthyroidism, according to Plummer's classification.2 In order to exclude any but true diabetic patients we used Joslin's standard for diagnosis of diabetes in hyperthyroidism, which, as stated in his book, is a blood sugar content of 0.15 per cent during fasting or of 0.20 per cent or more after meals, in addition to glycosuria.

Table 1 shows the frequency of occurrence of diabetes combined with hyperthyroidism. A comparison is made with the figures

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