Since the publication of Schlagenhaufer's work in 1913, studies of gastro-intestinal lymphogranulomatosis, particularly of the localized type, have been made from the clinical and pathologic points of view, and from these the basis of the present conception regarding this type of Hodgkin's disease has been formed. Cases of Hodgkin's disease of this type warrant particular attention as the formulation of the correct clinical diagnosis is extremely difficult, notwithstanding the numerous laboratory procedures available. The diagnosis is usually made after operation or at necropsy on the basis of the histologic picture and not on that of the gross anatomic features, which cannot be differentiated from those of other pathologic conditions. Two additional cases are here presented, and an analysis is made of the available clinical data regarding seventy-three cases reported in the literature.
In 1889 Pitt described lesions in the stomach and duodenum as part of generalized Hodgkin's disease. Wells and