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ARTICLE |

Experimental Studies on a Transmissible Myelomatosis (Reticulosis) in Mice.

Arch Intern Med (Chic). 1937;59(2):365-366. doi:10.1001/archinte.1937.00170180192009.
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ABSTRACT

This monograph combines an excellent review of the literature concerning leukotic conditions in mice and guinea-pigs and the results of extensive and thorough experiments by the author. It has been fairly well established in the literature that leukosis in fowls can be transmitted by cell-free filtrable agents and that transmissible leukosis and filtrable sarcoma of fowls have many properties in common. Mammalian leukosis has, however, been transmitted only by means of living cells. The overwhelming majority of the transmissible mammalian leukoses hitherto described either have been or have been conceived as being lymphatic. Only in the last year or so (Furth and others) have reports appeared showing the existence of transmissible myeloid leukosis in mammals. The author's experiments are concerned with the transmissibility of myeloid leukosis (myelomatosis). The use of mice of genetically pure strains is important for successful transmission. However, insusceptibility to implantation of leukotic cells can in

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