Karsner's "Human Pathology" has been accepted widely as a text by teachers, students and practitioners of medicine. The fourth edition, now offered, has been revised and extended to include some of the more recent advances in pathology. Certain chapters have been rewritten completely. The general plan of arrangement is essentially the same as in the preceding editions. The twelve chapters of the first part concern general pathology; the ten of the second part are special. The preceding editions have been used largely by undergraduate students of medicine and has been an excellent text for them. The fourth edition will serve the same general group and is recommended to instructors of general and special pathology in medical schools for the guidance of their students.