This monograph presents a thorough and extensive investigation of the aspiration method (Arinkin) of obtaining bone marrow for biopsy. The literature is thoroughly reviewed. The experiments of other investigators were painstakingly repeated. One hundred and ten normal persons and seventy-five persons with pathologic conditions were studied.
The simplicity of this technic commends itself for clinical use (an article describing an almost identical technic of bone marrow puncture appeared in a recent issue of the Archives of Internal Medicine55:186 [Feb.] 1935). The loss of structural relationships in the marrow so removed is the only limitation of the method that does not apply to other methods of obtaining marrow for biopsy. In this method, as in others, there is an indeterminable admixture of peripheral blood and specific bone marrow elements. Segerdahl confirms the findings of Tuschinsky and Kotlarenko that the greater the amount of material aspirated the greater the dilution