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De Venarum Ostiolis 1603 of Hieronymus Fabricius ab Aquapendente (1533?-1619).

Arch Intern Med (Chic). 1935;56(1):208. doi:10.1001/archinte.1935.03920010216011.
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The pamphlet on the valves of the heart of twenty-three pages was described as but one of the "remaining pamphlets, and of that large work, which we are compiling on the structure of the animal as a whole" (Fabricius). It is thus but a chapter of a contemplated work on the anatomy of the body which was never completed. Fabricius observed that he noted the valves first in 1574 and demonstrated them to his students, including William Harvey, before he published his account of them in 1603—the year after Harvey left Padua. According to Boyle, Harvey, in a private conversation, confided to him "that when he took notice of the Valves in the Veins of so many several Parts of the Body Towards the Heart, but opposed the passage of the Venal Blood the Contrary way: He was invited to imagine... That, since the Blood could not well, because of


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