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Some Factors in the Localisation of Disease in the Body.

Arch Intern Med (Chic). 1933;52(1):164. doi:10.1001/archinte.1933.00160010171023.
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This is a unique work that wanders in a highly speculative field and at the same time makes practical use of its material. The title is a bit misleading. One would suspect that the book dealt with the reasons why diseases selected certain portions of the body for their point of attack. This is true, but the author also discusses the limitation of disease processes, secundum artem, using the knowledge gained in studying the various biologic and physiologic tissue changes both in experimental animals and in patients. The study of these changes takes the author into the fields of biology, physics, chemistry and electricity. With much of this work as a basis, new conceptions must be built up concerning certain ill-understood diseases. The author mentions in this connection epilepsy, puerperal sepsis and chronic arthritis.

The book deals first with the localization of foreign proteins, dyes, pigments, syphilis, bacteria, virus and


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