The rapid development of travel by airplane has brought to a large number of people a new physiologic environment. A few years ago only the professional balloonist and the mountain climber were subjected to high altitudes, but in recent years the number of people who are subjected to anoxemia has been steadily increasing. From this point of view alone the effect of low oxygen tension on the stomach would be of interest. This combined, however, with the fact that anoxemia is also caused by the various anemias, by diseases of the circulation and of the lungs makes the problem still more interesting. It is well known, for example, that gastric disturbances are not uncommon with cardiac disorders.
It was shown by the authors of this paper in 19301 that hunger contractions in the normal dog were greatly decreased in anoxemia. In a subsequent paper2 it was shown that