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ARTICLE |

UREA CLEARANCE TEST AS AN INDEX OF RENAL FUNCTION:  IV. THE UREA CLEARANCE TEST IN RELATION TO OTHER TESTS AND MEASURES OF RENAL FUNCTION

MAURICE BRUGER, M.D.; HERMAN O. MOSENTHAL, M.D.
Arch Intern Med (Chic). 1932;50(4):556-568. doi:10.1001/archinte.1932.00150170048004.
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The urea clearance studies in twenty-one cases of Bright's disease, which formed the nucleus of the preceding paper in this series,1 will be correlated in the following pages with various other tests and measures of renal function. Van Slyke, McIntosh, Möller, Hannon and Johnston2 and Johnston3 have compared the urea clearance with the concentrations of urea, uric acid, creatinine and hemoglobin in the blood, the excretion rate of phenolsulphonphthalein and the urea concentration ratio in nephritic subjects. Our work permits us to compare our findings concerning the blood urea clearance in subjects with Bright's disease with the concentrations of urea, uric acid and creatinine in the blood, the blood count (hemoglobin and red blood cell count), the two hour test for renal function and the urea concentration ratio urine urea concentration blood urea concentration

METHODS  Urea in blood and urine was determined by the gasometric urease method of Van Slyke,4

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