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RELATIONS BETWEEN PRIMARY HYPOCHROMIC ANEMIA AND CHLOROSIS

ARTHUR L. BLOOMFIELD, M.D.
Arch Intern Med (Chic). 1932;50(2):328-337. doi:10.1001/archinte.1932.00150150160015.
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Under the designation of hypochromic anemia1 (primary, microcytic, idiopathic, achylic) there have appeared in the recent literature2 a number of reports. They concern themselves with a disorder featured by an anemia with a low color index and small erythrocytes, and usually by gastric anacidity, which occurs almost exclusively in women in from the third to the fifth decade. The implication of most of the current writings is to the effect that this syndrome is a specific disease; some authors (Witts,3 Dameshek,4 Mills5 and Vanderhoof and Davis6) have definitely stated that such is their belief. Furthermore, although this is admitted to be a chlorotic type of anemia, it is usually claimed that it is not chlorosis but rather an entirely distinct entity. That chlorosis, so common in the practice of physicians a generation ago, should have vanished and that a new type of chlorotic anemia should have

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