0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

SOME IMMUNOLOGIC ASPECTS OF LEUKEMIA

W. C. HUEPER, M.D.; MARY RUSSELL, M.S.
Arch Intern Med (Chic). 1932;49(1):113-122. doi:10.1001/archinte.1932.00150080116008.
Text Size: A A A
Published online

Investigations of Carrel and Elbeling1 into the proliferative activity of blood leukocytes in tissue cultures have shown that homologous serum possesses a marked antiproliferative effect on polymorphonuclear leukocytes and lymphocytes. The first mentioned type of white blood cell disappears entirely from the culture in a few days, and the latter type in from one to two weeks. By a process of physiologic selectivity a pure culture of mononuclear cells remains, which can be kept alive for several months. Carrel and Ebeling concluded from this observation that homologous serum may possess a similar action in vivo, because the number of leukocytes would increase indefinitely if serum were not endowed with this property. They added that probably the increase of the growthinhibiting action of serum in the course of life determines a decrease in the activity of the white cells and modifies their secretions. They suggested, moreover, that possibly this is

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();