After a brief historical introduction, the author discusses briefly the pharmacognosy and chemistry of quinine as well as the fate of the drug after absorption. By far the greater part of the book is given over to a consideration of therapeutic uses of quinine in diseases other than malaria, which is discussed in less than a dozen pages. From the evidence presented, one may gain the impression that quinine is indicated in a great variety of infectious diseases (pulmonary diseases, pertussis, erysipelas, etc.). However, surprisingly few authors who do not attribute their success to quinine or who have obtained untoward results are cited in the detailed discussion of many diseases which one rarely associates with quinine therapeutically. The author also cites numerous references to the use of the drug in disturbances of cardiac conduction, in the initiation of labor and in the treatment for varicose veins and hemorrhoids.