0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

I. GOLDSTEIN'S HEREDOFAMILIAL ANGIOMATOSIS WITH RECURRING FAMILIAL HEMORRHAGES (RENDU-OSLER-WEBER'S DISEASE)

HYMAN I. GOLDSTEIN, M.D.
Arch Intern Med (Chic). 1931;48(5_I):836-865. doi:10.1001/archinte.1931.00150050117011.
Text Size: A A A
Published online

In the opening paragraph of his paper on "Gastric Hemorrhage Due to Familial Telangiectasis," Boston1 stated:

A cursory survey of the literature disclosed records of 3 cases of recurrent rectal hemorrhage, one of oral bleeding and one of hematemesis which had been accompanied by cutaneous telangiectases. Wilson gave us the first recorded instance of rectal bleeding from telangiectases in 1896; Fox recorded a case in 1908; Phillips in 1908 cites the case of an extensive telangiectasis of the skin and mucous surface of the mouth with hemorrhages from the pharynx, and possibly from the stomach. Hutchison and Oliver's patient experienced recurrent rectal hemorrhage; and Pringle in describing his case alludes to recurrent attacks of vomiting blood.

Boston stated further that telangiectasia has not been considered in connection with painless hemorrhage of either gastric or rectal origin, and that the familial etiologic nature of the disease is evidenced in the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();