0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

THE ALKALINE TIDE AS A METHOD OF STUDYING GASTRIC ACIDITY

ROGER S. HUBBARD, Ph.D.
Arch Intern Med (Chic). 1930;46(6):994-1001. doi:10.1001/archinte.1930.00140180095009.
Text Size: A A A
Published online

In 1926 a series of tests on the urine of patients suffering from achlorhydria was reported.1 It was shown that little or no increase in alkalinity developed in such subjects after a standard meal, but that when normal subjects used as controls were studied by the same technic, the urine usually showed an alkaline tide; that is, it became more alkaline than it had been before the meal. The difference between the two types of cases was clearly shown by the average figures. This indicated that the secretion of hydrochloric acid by the stomach was the usual cause of the increase in alkalinity observed, as had been claimed by many observers since Bence-Jones2 first described these variations in acidity.3 Similar work by Ackman4 and Davies5 has furnished confirmation of this thesis.

In addition to these studies of the physiology involved, it was suggested that the test might be adapted to

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();