TOXIC ADENOMA OF THYROID

A review of the literature shows that toxic adenoma of the thyroid has been considered under a variety of names. Some of these synonyms are:

Enlargement of the thyroid gland in connection with enlargement or palpitation of the heart—Parry¹ (1825).

Constitutional iodism—Rilliet² (1859).

Iodine exophthalmic goiter; iodine Graves' disease—Trousseau³ (1860).

Formes frustes exophthalmic goiter—Trousseau⁴ (1862); Marie⁵ (1883).

Secondary Basedow—Gauthier⁶ (1893); Buschan⁷ (1894).

Basedowified goter—Marie⁸ (1897); Struma basedowificata—Kocher⁹ (1906).

Goiter heart—Kraus¹⁰ (1898).

Iodine thyroidism—Breuer¹¹ (1900).

Basedowid—Stern¹² (1908-1909).

Toxic nonexophthalmic goiter—Plummer¹³ (1912).

Toxic adenoma of the thyroid—Plummer¹⁴ (1913).

Adenoma with hyperthyroidism—Plummer¹⁵ (1916).

Hyperfunctioning adenomatous goiter—Plummer¹⁶ (1921).

Iodine hyperthyroidism—Jackson¹⁷(1924).

Nodular goiter with hyperthyroidism—Rienhoff¹⁸ (1927).

In a recent study of the goiter problem, Aschoff¹⁹ stated: "We were able to show that the nodular form was not a kind of hyperplasia or hyperplastic condition, as was then believed, but that we were dealing with a definite tumor formation, namely, adenomata." Do simple adenomas of the