In this paper, we present the data obtained from the study of blood drawn from a series of human addicts receiving morphine sulphate hypodermically in sufficient quantity to prevent withdrawal symptoms. All of these addicts exhibited the so-called withdrawal symptoms on cessation of administration of the drug. These symptoms have been described in a previous paper by us1 and are well known to any one familiar with the drug problem. Our purpose in this study has been twofold. The first objective was to search for possible changes in the physicochemical properties of the blood of these addicts; our second, to obtain values in addicts receiving the drug for comparison with the results obtained from the same addicts following the withdrawal of the drug.
During this study the addict received the quantity of drug required, which was administered to him by the nurse in charge of the ward. As