In 1920, Drey and Lossen1 treated a patient who was afflicted simultaneously with leukemia and bronchial asthma by irradiation of the spleen with the roentgen ray; they noticed that the asthmatic condition improved appreciably. Similar reports of the recovery of asthmatic patients following irradiation administered to alleviate other ailments are given by Scott2 and Schilling.3 In 1925, Groedel4 treated a number of asthmatic patients by irradiation of the spleen and was favorably impressed with the results. Others (Pohlmann,5 Gallino and Terrada6 and Moner7 concurred in the optimistic opinions of the foregoing authors on the value of this form of therapy.
In this country, Gerber8 introduced this procedure for the treatment of patients with asthma, and at the same time advocated exposure of the chest, the so-called direct method, which is based on the previous work of Klewitz,9 Schilling3 and others.
Cole and Ramirez,10 who applied roentgen-ray treatment over the spleen