This monograph of fifty-seven pages is the address by the author on the occasion of his induction into the Royal Academy of Medicine of Seville. It is profusely illustrated with polygraph tracings and electrocardiograms, representing the results of the study of twenty-two cases of auricular fibrillation and flutter.
Most of the paper is taken up with a discussion of the action of quinidine in these cases. His review of the literature shows that of 379 patients treated with this drug, the normal rhythm was restored in 190, almost exactly half. On the basis of the circus movement theory of Mines and Garry, which has been elaborated by Lewis and Mackenzie, he has attempted to explain the action of the drug. While digitalization can produce an improvement in the rhythm by bringing on heart block, quinidine action on the auricle itself, by the prolongation of the refractory period, may bring it