0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

THE UNITARY NATURE OF IMPAIRMENT OF RENAL FUNCTION

ARTHUR M. FISHBERG, M.D.
Arch Intern Med (Chic). 1926;38(2):259-275. doi:10.1001/archinte.1926.00120260117010.
Text Size: A A A
Published online

Nearly a century has elapsed since Richard Bright made his celebrated "statements and conjectures regarding the dependence of a peculiar class of Dropsies on disease and irritation of the Kidneys."1 Since then numerous additions have been made to our knowledge of the symptomatology of Bright's disease, the most significant, perhaps, being arterial hypertension, albuminuric retinitis, and the so-called uremic phenomena largely involving the central nervous system. The systemic manifestations of kidney disease are so variegated, and their association with one another so inconstant, that it was early realized they could not all be due to the same pathogenetic factor. In attempts to explain the connection between the kidney lesions and the associated systemic phenomena, two main paths have been pursued:

1. The study of extrarenal factors. This dates back to the classic investigations of Gull and Sutton2 on cardiac hypertrophy and Cohnheim and Lichtheim3 on edema. In the case of

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();