This volume covers a wide range of activities, including bacteriology, chemistry and pathology, and the imposing character of the work reported cannot fail to impress one with the great importance of this research institute. The present report contains nineteen articles covering 241 pages, with profuse illustrations. Many of these papers are simply résumés of one or more far more elaborate articles originally published only in Japanese. Here all are translated into English or German, with one in French.
Of special note is the summary of the research by a number of workers on tsutsugamushi disease. By intradermal inoculation of blood from infected patients they have reproduced the disease typically. The causative organism is proved to be nonfiltrable and nonculturable on all ordinary mediums. It can be transmitted only by the bite of a small mite, Trombicula akamushi. The offending organism is multiform, having monococcal, diplococcal and bacillary forms, and cannot