This well written monograph concerning arthrosyphilis tardiva is the first of a series devoted to syphilis and internal medicine. The two parts in preparation will deal with the relation of syphilis to other internal diseases and to the glands of internal secretion.
The present work, based on a study of thirty-five cases, describes the hitherto largely neglected forms of joint conditions due to syphilis in which other signs of syphilis are absent. The Wassermann reaction of the blood is of no value in diagnosis since it usually is negative and frequently remains negative throughout treatment. A positive reaction of the joint fluid, found in some cases, is of diagnostic significance. Luetin tests, also, are of no value. The writer believes that, exclusive of cases of septic origin, gonorrhea and late syphilis are the most frequent causes of the acute joint affections refractory to salicylates. Late syphilis is also responsible for