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QUINIDIN IN THE TREATMENT OF AURICULAR FIBRILLATION, ESTABLISHED, PAROXYSMAL AND TRANSIENT

F. JANNEY SMITH, M.D.; NORMAN E. CLARKE, M.D.
Arch Intern Med (Chic). 1925;36(6):838-846. doi:10.1001/archinte.1925.00120180092009.
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In spite of the fact that quinidin has been widely used over a period of six years in the treatment of auricular fibrillation, there still exists a difference of opinion concerning its indications and contraindications, as well as its true value and dangers. It therefore seems worth while to add to the already existing reports of its use, so that more material may be available for determining our final opinion regarding the usefulness of this drug in complete arrhythmia.

TYPES OF AURICULAR FIBRILLATION  For convenience, cases of auricular fibrillation may be divided into three types: established, transient and paroxysmal.

  1. Established: In this type the abnormal rhythm has been present for more than two weeks and has shown no tendency to alternate with sinus rhythm, and the presence of the irregularity is not dependent on a transient contributory factor.

  2. Transient: This group includes the patients showing auricular fibrillation lasting from

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