According to the author's preface, the book "is intended principally for the general practitioner who feels the need of a short practical account of some of the newer methods employed in investigating renal function." The author has accomplished his purpose in a clear, concise and interesting manner. He is in an unusual position to do this since he has the point of view both of the investigator and the clinician of vast experience in this special field.
The accepted theories of renal function are discussed in relation to the actual findings in acute nephritis and in chronic nephritis, both of the azoremic and the hydremic types. Along with the changes in the urine, blood and tissues are given the findings relative to nitrogen, salt and water retention.
Histologic observations are presented and illustrated by colored plates. The significant remark is made "that the toxin causing the purely degenerative lesion of