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March 1925, Vol 35, No. 3 >
ARTICLE | March 1925

THE PROGNOSIS OF CHRONIC INFECTIOUS ENDOCARDITIS

ALFRED D. BIGGS, M.D.
Arch Intern Med (Chic). 1925;35(3):402-404. doi:10.1001/archinte.1925.00120090115010.
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According to reports in the literature, chronic infectious endocarditis is usually fatal. Billings,1 observed only one recovery in fourteen patients, and all of the ten reported by Osler2 died. Of the 150 patients with subacute bacterial endocarditis reported by Libman,3 146 died, and recently Thayer4 reported 206 cases terminating fatally. Contrasted with these are other statistics mentioning a lower death rate. Four patients treated with sodium cacodylate by Capps5 are reported well after three years. Graham, Ollie and Detweiler6 have observed twenty-three patients for a period of nine years, and of these at least twenty are living. The presence of bacteria in blood cultures of patients with endocarditis is generally regarded as indicating a grave prognosis. This idea is not altogether in harmony with results obtained at St. Luke's Hospital, Chicago. Of fifty-seven patients with bacterial endocarditis twenty-four are living and many of them seem to have recovered from the

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