NOTES ON THE THERAPEUTIC VALUE OF PNEUMOCOCCUS ANTIBODY SOLUTION SUBCUTANEOUSLY ADMINISTERED IN LOBAR PNEUMONIA

The work reported in this article is concerned with our findings at Long Island College Hospital, during the fall, winter and spring of 1923-1924, as a part of a clinical experiment with the subcutaneous administration of pneumococcus antibody solution pursued under the supervision of the influenza commission in the cities of New York, Boston, Cincinnati and Chicago. It seemed desirable to study the effect of antibody solution administered subcutaneously, largely because previous workers seemed to be agreed that the reactions following intravenous inoculation of antibody solution are often severe and sometimes actually dangerous to the patient. In the interests of uniformity and in order to provide comparable results, the experimental clinical work was pursued in accordance with the following plan outlined by the influenza commission.

SELECTION OF CASES 

1. Every case giving a typical history of chill, fever, pain in the side and cough with rusty sputum, together with typical