An ever widening foundation of biochemistry, biophysics and physiology form the basis of our understanding of pathologic processes and clinical manifestations of disease. To present an even superficial view of this vast fabric of interrelated basic phenomena in a single volume seems an almost hopeless task, the more so when it is to be made useful for students of medicine rather than the more mature. Krehl succeeded in a singularly striking fashion, due, no doubt, to his marvelous grasp of the material. We now possess three additional efforts in the same direction, those of Herring, of Ludke and Schlayer, and of Pfeiffer, here reviewed. In its subject matter Professor Pfeiffer's work is also a pathologic physiology.
There can be no doubt as to the importance of the subject or of the value of the systematic and orderly treatment of the material for the student. Teachers of medicine realize only too