0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

A COMPARATIVE STUDY OF THE PHENOLTETRACHLORPHTHALEIN AND HEMOCLASTIC TESTS OF LIVER FUNCTION

A. GONZALEZ, M.D.; W. G. KARR, Ph.D.
Arch Intern Med (Chic). 1924;34(3):282-291. doi:10.1001/archinte.1924.00120030017003.
Text Size: A A A
Published online

The early diagnosis of hepatic disease and of the type of lesion present is of the utmost importance. A slight enlargement of the liver with or without symptoms, or the occurrence of a group of symptoms pointing to hepatic disturbance, is not an uncommon finding. There are also some obscure abdominal conditions, in which even the diagnosis of the organ affected cannot be made conclusively. In all these cases a practical test of the liver function is a most welcome help in solving the problem.

Many clinical procedures have been described for detecting deranged hepatic function. The majority are based on one or more of the functions attributed to the organ,, but up to the present time few, if any, have been able to withstand a careful scrutiny.

In 1909, Abel and Rowntree,1 searching for an intravenous cathartic, noticed that when phenoltetrachlorphthalein was injected into experimental animals, most of the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();