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DIFFERENTIAL IMPROVEMENTS IN THE SYMPTOMS OF TOXIC GOITER DURING ROENTGEN-RAY TREATMENT AND REST

MARGARETE M. KUNDE, Ph.D.
Arch Intern Med (Chic). 1924;33(6):758-762. doi:10.1001/archinte.1924.00110300101005.
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The value of the basal metabolic rate as an index of the degree of toxicity in goiter has been fully discussed by Du Bois,1 Means,2 McCasky,3 Boothby4 and others. The influence of roentgen-ray treatment on the symptoms of toxic goiter appears to be variable. Halsted5 (1914) states that selected cases of exophthalmic goiter show improvement after treating the thymus gland with roentgen ray. Seymour6 (1916) briefly reports the effect of roentgen-ray treatment in eighty cases of exophthalmic goiter. All but seven of these patients showed marked improvement. Seymour concludes that the pulse rate is nearly always reduced at once, and that an increase in the body weight, improvement in nervous symptoms and tremors and a change in the size and condition of the thyroid gland occur almost immediately. Means and Aub2 (1919) report on a group of fifteen cases of exophthalmic goiter treated with roentgen ray in which the patients

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