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C. W. McClure, M.D.; O. C. MONTAGUE; L. L. CAMPBELL, Ph.D.
Arch Intern Med (Chic). 1924;33(4):525-532. doi:10.1001/archinte.1924.00110280123013.
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The present communication reports the results obtained from a study of PH and buffer values, the latter determined by electrometric titration, of duodenal contents derived from normal persons.

With the exception of the comparatively recent publications of McClendon1 and of McClure2 and their co-workers, there are no reported studies on the PH of duodenal contents collected during the period when intestinal digestion was definitely known to be in progress. The paucity of observations of this nature led us to make a somewhat more comprehensive study of the subject.

EXPERIMENTAL PROCEDURE  For the purposes of the recent investigation, duodenal contents were obtained from normal young men. The duodenal tube was taken before breakfast, fifteen hours after the last food intake and nine hours after the last drink of water. The tip of the tube was allowed to pass into the priximal end of the second portion of the duodenum, a distance


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