March 1924, Vol 33, No. 3 >

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ARTICLE | March 1924

THE OCCURRENCE AND SIGNIFICANCE OF THE "MYELOBLAST" UNDER NORMAL AND PATHOLOGIC CONDITIONS: PRELIMINARY ACCOUNT

HAL DOWNEY, Ph.D.

Arch Intern Med (Chic). 1924;33(3):301-313. doi:10.1001/archinte.1924.00110270022003.

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The following paper is a brief account of the results of several years of investigation of the subject indicated in the title. The complete paper with detailed discussion of the literature will be published in some European journal, because the numerous colored plates will have to be lithographed.

Naegeli¹ (1900) was the first one to express the view that the nongranular cells of the marrow are specific parenchymatous cells of this tissue which serve as the parent cells for the granular leukocytes. Naegeli stated emphatically that although they possessed some lymphoid characters, they differed from true lymphocytes in their morphologic and biologic characters, and that their origin was entirely separate from that of the lymphocytes.

But Naegeli was not the first one to express the theory of a polyphyletic origin of the blood cells, and he was not the first one to describe lymphoid cells in the marrow. Ehrlich² had

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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DOWNEY H. THE OCCURRENCE AND SIGNIFICANCE OF THE "MYELOBLAST" UNDER NORMAL AND PATHOLOGIC CONDITIONS: PRELIMINARY ACCOUNT. Arch Intern Med (Chic). 1924;33(3):301-313. doi:10.1001/archinte.1924.00110270022003.

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THE OCCURRENCE AND SIGNIFICANCE OF THE "MYELOBLAST" UNDER NORMAL AND PATHOLOGIC CONDITIONS: PRELIMINARY ACCOUNT

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