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Arch Intern Med (Chic). 1923;32(5):746-757. doi:10.1001/archinte.1923.00110230102009.
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Ordinarily staphylococcic septicemias present a fulminating septic picture classically represented by repeated chills, fever, delirium, purpura, endocardial murmurs and multiple abscesses. The blood picture shows a leukocytosis and an anemia. Cocci are easily grown from the blood by the ordinary cultural methods. The infectious focus may be a minute pyogenic skin infection, a furuncle, a discharging ear or a suppurating sinus. Of these foci, the most important are the sources from the skin. Such a pyemic state is represented by generalized multiple abscesses of the organs, more particularly minute suppurative foci in the kidneys, heart muscle and lungs. Commonly the mitral and aortic valves show large thrombus masses with rapid destruction of the leaflets. The muscles, the medullary cavities of the long bones or joints may show collections of yellowish pus, from which cocci are readily grown. A pyemia which represents the acute type described can be experimentally simulated in


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