Arch Intern Med (Chic). 1923;31(2):297-301. doi:10.1001/archinte.1923.00110140149014.
Text Size: A A A
Published online

Acute intestinal intoxication in infants has been generally regarded as due to an infection. The lack of any unanimity of opinion among workers in this field as to the responsible organism, lead us to consider the possibility of the toxemia being due to a chemical toxin, in the production of which various types of organisms might play a more or less important part. Schloss1 recently reported the finding of a substance of unknown nature in the blood of cases of intestinal intoxication which proved to be toxic to guinea-pigs.

Starling,2 in 1902, and later Popielski,3 reported the finding of a toxic substance in extracts of normal intestinal mucous membrane. This toxin, when injected into animals, caused a symptom complex consisting of increased peristalsis, periods of depression and narcosis, vasodilation, and fall of blood pressure. Barger and Dale4 regarded this substance as identical with the amine base β imino-azolylethylamine (histamine) which


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.