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ARTICLE |

PATHOLOGIC PHYSIOLOGY OF POLYCYTHEMIA VERA

RAPHAEL ISAACS, A.M., M.D.
Arch Intern Med (Chic). 1923;31(2):289-296. doi:10.1001/archinte.1923.00110140141013.
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Some features of the abnormal physiology of polycythemia vera (Vaquez or Osler's disease) were studied in a case in the medical wards of the Cincinnati General Hospital, on the service of Dr. Mark Brown.

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History.  —The patient (No. F.9928), a well developed man of 62, was in good health until five years ago. While on duty as a policeman, he was struck in the abdomen with an iron bar. One-half hour later he became weak and helpless and was taken to a hospital. The following day the abdomen was opened and the peritoneal cavity was found to be full of blood from a ruptured mesenteric artery. His recovery was uneventful, and he continued in fair health with occasional attacks of vertigo and headache. Some of his symptoms at that time led to a tentative diagnosis of tuberculous meningitis, but there was apparently nothing to substantiate this. He

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