December 1921, Vol 28, No. 6 >

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ARTICLE | December 1921

THE EFFECT OF THE EXTRACT OF THE POSTERIOR LOBE OF THE PITUITARY ON BASAL METABOLISM IN NORMAL INDIVIDUALS AND IN THOSE WITH ENDOCRINE DISTURBANCES

C. A. McKINLAY, M.D.

Arch Intern Med (Chic). 1921;28(6):703-710. doi:10.1001/archinte.1921.00100180021002.

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That there is an interrelation of the glands of internal secretion is well known. Rowntree¹ states that where life is, metabolism is, and regulating it are the endocrine glands. Kestner² states that all endocrine glands are closely related and that the most intimate relation exists between the thyroid and hypophysis. Engelbach³ mentions as a fact that the hypothyroid state is frequently associated with hypopituitarism. Peritz⁴ thinks that the intensive growth in length of bones which is sometimes found in exophthalmic goiter may be ascribed to a functional disturbance of the hypophysis. Holmgreen⁵ mentions that exophthalmic goiter patients in youth may show accelerated growth in height. Friedman⁶ believes that there may be a mild overactivity of the hypophysis in exophthalmic goiter and a mild underactivity in myxedema.

Numerous growth and feeding experiments give evidence of the relationship between the endocrine glands. Rogowitsch⁷ concluded that the changes in the hypertrophied hypophysis which

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McKINLAY CA. THE EFFECT OF THE EXTRACT OF THE POSTERIOR LOBE OF THE PITUITARY ON BASAL METABOLISM IN NORMAL INDIVIDUALS AND IN THOSE WITH ENDOCRINE DISTURBANCES. Arch Intern Med (Chic). 1921;28(6):703-710. doi:10.1001/archinte.1921.00100180021002.

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THE EFFECT OF THE EXTRACT OF THE POSTERIOR LOBE OF THE PITUITARY ON BASAL METABOLISM IN NORMAL INDIVIDUALS AND IN THOSE WITH ENDOCRINE DISTURBANCES

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