0
ARTICLE |

THE SIGNIFICANCE OF THE ACIDOSIS OF METHYL ALCOHOL POISONING

CHARLES C. HASKELL; S. P. HILEMAN; W. R. GARDNER
Arch Intern Med (Chic). 1921;27(1):71-82. doi:10.1001/archinte.1921.00100070074005.
Text Size: A A A
Published online

The increase in the number of cases of poisoning by methyl alcohol that has occurred recently renders particularly interesting the report of the favorable results obtained by Harrop and Benedict1 in the treatment of a case of such poisoning with sodium bicarbonate. The rationale of this treatment depends on the fact first demonstrated by Król2 that there is an abnormal excretion of acid bodies in the urine following the ingestion of methyl alcohol. Since Pohl3 had previously shown that methyl alcohol is slowly and incompletely oxidized in the body, a considerable proportion of that administered being excreted in the shape of formic acid, it was believed that this formic acid was responsible for the "acidosis." Król, however, found that the formic acid accounted for only a small part of the ammonia of the urine, indicating that other organic acids were excreted in abnormal amounts. Tyson and Schoenberg4 also found that

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Correspondence

CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 1

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs