We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......


Arch Intern Med (Chic). 1920;26(5):544-560. doi:10.1001/archinte.1920.00100050037003.
Text Size: A A A
Published online

The object of this paper is to record the results obtained from experiments on two patients with chronic pulmonary emphysema, of the so-called "large lunged" type. The work was undertaken in an effort to ascertain facts which might lead to a clearer appreciation of the disturbance in respiratory physiology in emphysema.

The gross and microscopic appearance of the lungs in this condition is well defined; also the impediment to the mechanics of respiration afforded by the loss of the elastic tissue of the lungs is appreciated. Further investigation, however, is necessary to show to what extent the degenerative process interferes with the aeration of the blood and the manner in which the body adapts itself to the altered conditions.

The work of Siebeck,1 Porges, Leimdorfer and Markovivi,2 Hoover3 and others established the fact that the residual air and the functional dead space are increased, while the vital capacity is much


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.