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Arch Intern Med (Chic). 1920;26(4):424-430. doi:10.1001/archinte.1920.00100040047004.
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During 1913 to 1919, 1,770 scarlet fever patients were treated at Durand Hospital, and cardiac complications were observed in 106. This does not include instances of increased rapidity nor occasional slight irregularity. A relatively rapid heart was common and slight irregularity, especially during the third and fourth weeks, was frequently noted, but was associated with no other appreciable alteration in the cardiac function.

Of the 106 patients recognized as exhibiting more definite cardiac complications, twelve had valvular defects antedating the scarlet fever. In the remaining ninety-four cases, a diagnosis of myocarditis was made in eighty-eight, of endocarditis in four and pericarditis in three. (One patient had both pericarditis and endocarditis.)

The cases of myocarditis have been classified as mild, moderately severe and severe. Mild cases were those with persistent feebleness, rapidity or irregularity of the pulse, but with little other disturbance. The moderately severe cases included those with a higher


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