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October 1920, Vol 26, No. 4 >
ARTICLE | October 1920

ON THE BEHAVIOR OF THE PYLORIC SPHINCTER IN NORMAL MAN

C. W. McCLURE, M.D.; L. REYNOLDS, M.D.; C. O. SCHWARTZ, M.D.
Arch Intern Med (Chic). 1920;26(4):410-423. doi:10.1001/archinte.1920.00100040033003.
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Systematic studies of motor phenomena of the normal gastrointestinal tract have been so largely carried out in the lower animals that but little detailed description of them in man is available. The results obtained from the studies in the lower animals can be applied only in a general way to the physiology of the digestive tract in man. It follows that more intimate knowledge concerning the motor phenomena of the alimentary canal in man would aid in the interpretation of results obtained from experimental studies of various phases of the pathologic physiology of human digestion. For this reason the work, with which the present report deals, was undertaken. It comprises observation on the behavior of the pyloric sphincter of the normal man in relation to various foodstuffs, and also to the presence of acid and alkaline solutions introduced into the stomach and duodenum of persons whose gastro-intestinal tracts were considered

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