During the past five years our knowledge regarding the content of inorganic phosphates in blood has been advanced by the work of several investigators: Taylor and Miller,1 Greenwald,2 Marriott and Howland,3 Feigl4 and Bloor5 have published the results of determinations of the inorganic phosphate content of plasma. Each investigator has worked by a different method, but, with the exception of the results obtained by Taylor and Miller, who state that the inorganic phosphate content of plasma is so small as to be negligible, the average values reported by the other workers are within the same general range.
In certain cases of nephritis, Greenwald and Marriott and Howland have reported the presence of greatly increased amounts of inorganic phosphates in plasma, the importance of which finding, in connection with both the theoretical and practical aspects of nephritic acidosis, has been pointed out by the latter workers.
More than a year ago,